Both of these aren't exactly what you're looking for, but they are excellent fics:

Pro Re Nata (http://teashopmuses.livejournal.com/10682.html) - Depression isn't always angst and sadness. Sometimes it's anger and dismissal and even humor. Dean's had clinical depression for years. Sam and Castiel find out.
Subterranean Homesick Blues (http://break-kitkat.livejournal.com/8915.html) - Fill for a prompt: Unknown to Sam, Dean has been reliant on anti-anxiety medication since he got back from Hell. [...] One day he wakes up to find that Sam has thrown out all his pills, painkillers, tranqs and booze: he's decided it's time for his brother to sober up. Dean tries to warn him how bad things will get, but Sam still isn't prepared for what happens.

Thank you!

There's also the Jensen Inside 'Verse (http://glassyskies.livejournal.com/?skip=60&tag=jensen%20inside%20%27verse) by glassyskies

ETA: Just thought of this one: Find Your Kindness (www.fanfiction.net/s/5767465/1/) by Baroqy. Sam knows about the law, researching, demons, weapons and saying 'no' to Lucifer. He's clueless as to how he's going to help with Dean's depression.

Urg, sorry for all the edits, LJ is being mean to me. In case you get a page not found page, this is the link to Find Your Kindness: www.fanfiction.net/s/5767465/1/

Edited 2012-06-10 05:53 pm (UTC)

Thanks, and don't worry about the edits. *kicks LJ*