I am so your girl for this.

Here There Be Tygers (http://kalliel.livejournal.com/206457.html)by kalliel: "The problem with Dean's memory is, it means he asks that question about eight trillion times more ("Sammy, are you okay? well, are you?") and as far as Sam's concerned, the answer matters even less. The problem with Dean's life is, it's supposed to end this year. And the problem with Dean's brother, well. Sam's still working on that one." (gen; I'm reccing this one all over the place today)

The Firefly That Loved Metallica (http://fleshflutter.livejournal.com/3749.html) by fleshflutter: "In which Sam has a bottle full of soul." (Sam/Dean)

The Descent of Inanna (http://vaingirlfic.livejournal.com/32303.html) by vaingirlfic: "Sam gets Dean out of his deal by making a worse one. It's like kidfic in a way." (Sam/Dean, lots of warnings and mindfuckery, and one of my very very favorites)

We Came From the Breeze (http://lazy-daze.livejournal.com/486002.html?format=light) by lazy_daze: "Have some post-hell amnesia fic!" (Sam/Dean)

Three Days on the Rack (http://archiveofourown.org/works/221235) by keerawa and reena_jenkins: "It’s been months, but Sam finally found a crossroads demon willing to Deal to get Dean’s soul out of Hell. The Deal sounded too good to be true. Sam took it anyway." (Sam/Dean, potential triggers out the wazoo)

The Year of Letting Go (http://runedgirl.livejournal.com/32053.html) by runedgirl: "A hunt gone wrong leaves Dean Winchester barely alive, and helpless for the first time in his life. Can Dean let go of his need to be the big brother and let Sam help him heal, or will the complicated feelings both brothers have been hiding from each other pull them further apart than ever? As Dean’s deal comes due, both Sam and Dean will have to let go of their fears, or face losing each other forever." (Sam/Dean)

Regrets Trilogy (http://samdean.archive.nu/series.php?seriesid=95) by jassy: "Sam refuses to allow the Crossroads Demon to have his brother." (Sam/Dean)

One Moment of Knowing That (http://kroki-refur.livejournal.com/174637.html) by kroki_refur: "As Obelix would say, if you're off your food, you're ill. Of course, he never met the Winchesters." (gen)

I don't know how you feel about fanvids, but The Other Side (http://archiveofourown.org/works/838289/chapters/1597321) by astolat is unlike any fanvid I've ever seen: "A hunt for a dragon in New York City ends with some unexpected changes for Sam and Dean. With the clock ticking down on Dean's deal, can the brothers pull together to save the city?" (The movie is gen, and there's a follow-up fic called Mystery Dance (http://archiveofourown.org/works/989550) by balder12 that is Sam/Dean and wonderful)

Life as We Know It (http://sevenfists.livejournal.com/113120.html) by sevenfists (and follow-up fic, The Taste of Apples (http://archiveofourown.org/works/283711) by rosekay) is a AU domestic fic where Sam saved Dean, though the focus is much more on the domesticity and the growing wincestuous tension than on the specifics of what went down. (Sam/Dean)

Keep Our Minds on the Sum of Each Other (http://lazy-daze.livejournal.com/452858.html?format=light) by lazy_daze is a Sam/Dean bodyswap fic where Sam talked Dean's way out of Hell. :)

Death Like Dying (http://archiveofourown.org/works/189790) by sobrecogimiento: "After Sam gets Dean out of hell, Dean doens't remember anything except Sam. And that means anything. So Sam has bundles of fucking joy trying to deal with it." (Sam/Dean)

Crush (http://sonofabiscuit77.livejournal.com/18531.html) by sonofabiscuit77: "Five years after the apocalypse didn’t happen and Sam and Dean have settled down, or as much as the Winchesters can ever settle down. Sam is a college professor and Dean a well-respected small business owner and they’re learning how to balance work, hunting and dog-ownership while coping with the metaphorical and literal scars of war. Life’s not perfect, not for a (sort of) out and proud couple in small town USA with a lot to hide, but they’re dealing, that is, until Dean employs one sexually-confused teenager who develops an unhealthy obsession with both of them... Switching between five years earlier and now, we learn how the boys came together, how they made it through the big fight and whether they’ll ever manage to find that flighty temptress, happily ever after." (Sam/Dean; to be completely honest, I'm not 100% sure whether Sam saves Dean here or Castiel does, but either way Sam's a huge part of the processes and sacrifices plenty along the way)

And the ending is ambiguous in this one, but it's wonderful anyway - Route 66 (http://spn-heraea.livejournal.com/3846.html) by sevenfists (Sam/Dean).

And a couple crossovers - Defect (http://www.fanfic.otherplaces.net/defect.htm) by kikkimax (gen; SPN/Criminal Minds) and Old Country (http://archiveofourown.org/works/164479) by astolat (Sam/Dean, SPN/Harry Potter)