No matter what series
http://archiveofourown.org/series/236673

Not meant to be
http://archiveofourown.org/works/2309393/chapters/5081558
Sam decides to keep their relationship professional, he stops seeing Dean as his lover and smothers the bond they share. Dean starts to eat less, sleep less and only focus all his effort on hunts as that is the only time he is able to get any kind of interaction time with Sam.

Since an omega's mental state of mind is dependent on the emotional care they receive from their Alpha through the bond, Dean's becoming mentally and emotionally drained. Unable to bear the pain any longer, Dean decides that it would be better for Sam if he's out of the picture.

The case of the omega and the alpha
http://archiveofourown.org/series/302109
Sam is an alpha studying law at Stanford and is an omega rights activist. Dean is an omega who has been abused for years by their father. Dean is removed from his father's custody and Sam takes him in.

This work of fiction details a society where omegas are regarded as little more than animals. Sam tries to undo the damage society and their father caused Dean.


Don't you quit on me (unfinished)
http://archiveofourown.org/works/1765627/chapters/3777058
than one percent of the whole world's population is made up of Omegas, and most people regard them as precious things to be protected and cared for at all cost; but not Alastair. And if anyone knows that, it's Dean.

Dean was taken from them when he was just four years old, Sam's been looking for him for the last twelve years, building a pack, mating with a beautiful beta in that time. Sam knows what taking on an Omega means and he knows perfectly well that Dean's his brother...but what can he do? He needs Dean by his side and if this is the only way, so be it. But Dean's head's all messed up, he doesn't remember his old life, he doesn't remember Sam...should Sam tell him? Should Dean know, after everything he's been forced to live through, that his own Alpha is his own big brother?